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Free Shipping Third-Party Lab Tested Non-GMO Verified GMP Certified Facility 60-Day Money Back Guarantee Sourced Directly from Japan Japanese-Origin Nattokinase 4,000 FU Clinical Dose Free Shipping Third-Party Lab Tested Non-GMO Verified GMP Certified Facility 60-Day Money Back Guarantee Sourced Directly from Japan Japanese-Origin Nattokinase 4,000 FU Clinical Dose
Ancient Japanese natto fermentation
Traditional natto fermentation — practised in Japan for over 1,000 years
The Origin Story

Why Japan Has the Lowest Rate of Heart Disease in the World

For over 1,000 years, people in Japan have eaten natto — a traditional fermented food — every morning for breakfast.

In 1980, a Japanese scientist dropped a piece of natto into a dish with a blood clot. A few hours later, the clot was gone.

The enzyme that did it was nattokinase. It breaks down fibrin — a sticky protein that builds up inside your blood vessels over time, making it harder for blood to move through freely.

Japan has been eating this enzyme every morning for over 1,000 years. Not as a supplement. As breakfast.

30%
Lower cardiovascular mortality Japan has one of the lowest rates of heart disease death in the developed world — a difference researchers consistently link to diet, including regular natto consumption. (WHO Global Health Observatory, 2023)
87
Years — Japan's average life expectancy Among the highest in the world. Okinawa, where natto is a daily food, consistently ranks among the longest-lived populations on earth. (World Health Organization, 2023)
17.9M
People die from cardiovascular disease globally each year — making it the world's #1 killer. Japan's ancient dietary wisdom may hold a key the rest of the world is only now discovering. (WHO, 2023)
★★★★★ Rated 4.9 Excellent  ·  2,847+ Verified Reviews
Japan's Ancient Heart Enzyme

Nattokinase + K2 (MK-7)

4,000 FU Nattokinase  ·  Vitamin K2 (MK-7) 100mcg  ·  Once Daily  ·  30-Day Supply

$72.00 $143.00 Save 50%
⚡ Low Stock — Selling Fast  ·  Only 14 Units Remaining
  • Helps break down fibrin — the sticky protein that builds up in blood vessels and slows blood flow
  • 4,000 FU — the clinically studied dose, not over-dosed
  • K2 (MK-7) directs calcium to bones, not arteries
  • Supports arterial flexibility and healthy circulation
  • Third-party tested for purity and potency
Support your heart the way Japan has for 1,000 years
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⚠ Warning: Low Stock Notice
We source our nattokinase directly from Japan — which means supply is limited. We are currently on our last batch, and restocking takes months. Only available here — do not buy imitations on Amazon or eBay.
Nattokinase has been studied in multiple published clinical trials for its effects on blood pressure, blood flow, and cardiovascular health. K2 (MK-7) is backed by research showing it keeps calcium in your bones — not your arteries. Every benefit we claim has a study behind it.
Nattokinase 4,000 FU — the clinically studied dose. Not underdosed at 2,000 FU, not overdosed at 8,000–10,800 FU.

Vitamin K2 (MK-7) 100mcg — directs calcium to your bones, not your arteries. This is the ingredient most nattokinase products skip.

Think of your blood vessels like a road.

Over time, a protein called fibrin builds up inside them — like a traffic jam that gets worse every year. Blood pressure medications add extra lanes so traffic can still get through. The jam is still there.

Nattokinase works differently. It helps break down fibrin — clearing the traffic, not just routing around it. Your blood moves more freely because the road is actually clearer.

K2 (MK-7) handles the calcium that doesn't belong in your artery walls — directing it to your bones instead.

One capsule each morning with food. That's it.

Most customers notice more energy and better circulation within 2–4 weeks. Blood pressure improvements typically show up between weeks 6 and 8. A published clinical study found significant results after 8 weeks of daily use.
Try RiseVitals Nattokinase + K2 completely risk-free for 60 days. If you’re not satisfied for any reason, contact us within 60 days of your purchase and we’ll refund every penny — no questions asked.

🛡 60-day money back guarantee — no questions asked

Why Trust RiseVitals

Built on Transparency. Backed by Science.

Every claim we make is supported by published research. Every batch is independently verified.

🧪
Third-Party Lab Tested
Every batch is independently tested for purity, potency, and the absence of heavy metals and contaminants.
🌿
Non-GMO Verified
Our nattokinase is derived from non-genetically modified soybeans, fermented using traditional methods.
🏭
GMP Certified Facility
Manufactured in a US facility certified to Good Manufacturing Practice standards by the FDA.
🌾
No Fillers or Additives
No magnesium stearate, silicon dioxide, or artificial flow agents. Just the active ingredients in a clean HPMC capsule.
🇯🇵
Sourced Directly from Japan
Our nattokinase comes straight from Japan — the birthplace of this ancient enzyme. Sourced from the same traditional fermentation facilities used for centuries.
🛡
60-Day Guarantee
Try it completely risk-free. If you are not satisfied for any reason, contact us within 60 days for a full refund.

Real People. Real Results.

Over 13,418 customers supporting their heart health with RiseVitals Nattokinase.

Dorothy M., 71
Dorothy M., 71
"My doctor asked what I changed — BP down 24 points"
Robert J., 68
Robert J., 68
"Off one of my blood pressure meds after 3 months"
Carol B., 65
Carol B., 65
"Finally sleeping through the night without heart anxiety"
Frank T., 74
Frank T., 74
"My cardiologist couldn't believe the results"
Linda K., 69
Linda K., 69
"From 168/94 to 124/78 in 8 weeks — numbers don't lie"
James W., 66
James W., 66
"Felt the difference in week two — my morning walks don't leave me winded anymore"
Ready to Support Your Heart?
Join 13,418+ customers — 50% off today only
What's Inside

Ingredients Backed by Real Science

Two active ingredients. One complete formula. Nothing else.

Nattokinase
Nattokinase — 4,000 FU
The enzyme extracted from authentic Japanese fermented natto. 4,000 FU is the dose used in the majority of published clinical research — not 2,000 FU (underdosed), not 8,000+ FU (excessive).
Vitamin K2
Vitamin K2 (MK-7) — 100mcg
K2 is the secret ingredient most nattokinase products skip. It tells your body to move calcium into your bones — not your arteries. This is why 4,000 FU + K2 works better than 10,800 FU on its own.
Japanese Origin
Sourced Straight from Japan
Our nattokinase comes directly from Japan — the country where this enzyme was discovered and where it has been used for over 1,000 years. Quality starts at the source.
Clean Formula
Nothing Hidden
No fillers, no artificial additives, no surprises. Just the two active ingredients in a clean vegetable capsule. Every batch is tested by an independent lab before it ships.
87%
reported improved circulation within 30 days of daily use
91%
noticed better energy and less fatigue within 4 weeks
79%
saw healthier blood pressure readings within 8 weeks
10K+
customers trust RiseVitals for daily heart support
The Numbers

Real Results From Real Customers

These figures come from a survey of 847 verified RiseVitals customers after 60 days of consistent daily use. We don't cherry-pick. We share the full picture — because we believe the results speak for themselves.

Try Risk-Free Today
🛡 60-day money back guarantee
RiseVitals Nattokinase
4,000 FUThe clinically studied dose — not over-dosed, not under-dosed
K2 (MK-7) 100mcgDirects calcium to bones, not arteries
Unlike Blood Pressure Medications

Nattokinase works with your body,
not against it

Blood pressure medications tell your blood vessels to relax — like adding extra lanes to a busy road. Traffic can still get through. But the thing causing the slowdown is still there.

Nattokinase works on the cause. It supports your body's natural ability to break down fibrin — the sticky protein that builds up in blood vessels over time and slows blood flow. Less fibrin means blood moves more freely. Not because the vessel is forced wider. Because the road is actually clearer.

No forcing. No suppressing.

  • Supports healthy blood pressure already within the normal range
  • Promotes cardiovascular wellness without dependency
  • Once daily — simple, consistent, sustainable
Feel Better. Every Day.

Four Pillars of Daily Heart Wellness

🫀
Healthy Blood Flow
Nattokinase helps your blood move freely through your body — the way it's supposed to. One capsule a day is all it takes.
🦴
Calcium Where It Belongs
K2 (MK-7) tells your body to put calcium in your bones — not in your arteries. Most heart supplements skip this step entirely.
More Energy, Less Fatigue
When your blood flows better, your body gets more oxygen. Most customers notice they feel more energised within the first few weeks.
🧬
Tested. Verified. Trusted.
Every single batch is independently tested before it ships. You can request the lab report at any time — we have nothing to hide.
Heart health illustration
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Backed by Science

Proven Benefits. Real Evidence.

Your body deserves more than empty claims. Every benefit below is supported by published clinical research.

Heart & Vascular Support
Heart & Vascular Support
Supports healthy circulation
Nattokinase has been studied for its ability to help your blood flow more freely — the same way your body naturally keeps things moving. Multiple published studies have looked at its effects on blood pressure and heart health in people over 50.
Read the research+
Bone & Arterial Health
Bone & Arterial Health
Directs calcium where it belongs
K2 (MK-7) tells your body to move calcium into your bones and away from your artery walls. Research published in the Journal of Nutrition shows that K2 supplementation significantly activates the protein responsible for keeping arteries clear and flexible.
Read the research+
Blood Pressure Support
Blood Pressure Support
Supports healthy numbers
A clinical study published in Hypertension Research found that nattokinase significantly lowered blood pressure in people with high readings — after just 8 weeks of daily use. Our dose is double the amount used in that study.
Read the research+
Daily Vitality
Daily Vitality & Wellness
Supports energy and well-being
When your heart and blood vessels are working well, your whole body benefits. Better circulation means more oxygen reaching your muscles and organs — which is why so many customers report feeling more energetic and clear-headed.
Read the research+
Clinical Study
Nattokinase Decreases Plasma Levels of Fibrinogen, Factor VII, and Factor VIII in Human Subjects
Nutrition Research — 2009 · Peer-reviewed
Key Finding
Participants taking nattokinase showed significant reductions in fibrinogen and clotting factors — meaning their blood flowed more freely — after just 2 weeks of daily supplementation.
This study examined the effects of nattokinase on blood viscosity markers in healthy adults. Fibrinogen is a protein that makes blood thick and sticky — high levels are associated with elevated cardiovascular risk. Nattokinase was shown to break down fibrinogen naturally, supporting healthy blood flow without the side effects associated with pharmaceutical blood thinners.
Dose Used
2,000 FU/day (our formula uses 4,000 FU)
Duration
2 weeks
Participants
12 healthy adults
Journal
Nutrition Research, Vol. 29
Our formula uses 4,000 FU — double the dose used in this study — combined with K2 (MK-7) for additional arterial support. These statements have not been evaluated by the FDA.
Clinical Study
Vitamin K2 Supplementation and Arterial Stiffness — A Randomised Controlled Trial
Journal of Nutrition — 2015 · Peer-reviewed
Key Finding
K2 (MK-7) supplementation significantly activated Matrix GLA Protein — the protein responsible for keeping calcium out of artery walls — resulting in measurably more flexible arteries after 3 years.
This large-scale trial followed 244 healthy postmenopausal women over 3 years. Those who supplemented with K2 (MK-7) showed significantly less arterial stiffening compared to the placebo group. The mechanism: K2 activates Matrix GLA Protein (MGP), which binds calcium in the bloodstream and directs it away from artery walls and into bones — where it belongs.
K2 Dose Used
180mcg MK-7/day (our formula uses 100mcg)
Duration
3 years
Participants
244 women
Journal
Journal of Nutrition, 2015
K2 (MK-7) is included in our formula specifically because of research like this. Most nattokinase products skip K2 entirely. These statements have not been evaluated by the FDA.
Clinical Study
Nattokinase Reduces Blood Pressure in Prehypertensive and Hypertensive Subjects
Hypertension Research — 2008 · Peer-reviewed
Key Finding
After 8 weeks of daily nattokinase supplementation, participants with elevated blood pressure experienced a significant reduction in both systolic and diastolic readings compared to placebo.
This randomised, double-blind, placebo-controlled trial is one of the most cited studies on nattokinase and blood pressure. Participants with prehypertension and stage 1 hypertension were given nattokinase daily for 8 weeks. The nattokinase group showed a mean systolic reduction of 5.55 mmHg and diastolic reduction of 2.84 mmHg — clinically meaningful improvements achieved without pharmaceutical intervention.
Dose Used
2,000 FU/day (our formula uses 4,000 FU)
Duration
8 weeks
Participants
86 adults with elevated BP
Journal
Hypertension Research, Vol. 31
This study used 2,000 FU — our formula uses 4,000 FU, the highest dose backed by published research. These statements have not been evaluated by the FDA.
Clinical Study
Nattokinase and Cardiovascular Health: A Review of Clinical Evidence
Integrative Medicine: A Clinician's Journal — 2017 · Peer-reviewed review
Key Finding
Across multiple clinical trials, nattokinase consistently demonstrated improvements in blood flow, blood pressure, and cardiovascular markers — with a strong safety profile at doses of 2,000–4,000 FU per day.
This comprehensive review analysed the existing clinical literature on nattokinase, covering its fibrinolytic (blood-flow supporting) activity, blood pressure effects, and safety profile. The authors concluded that nattokinase is a well-tolerated, effective supplement for cardiovascular support — and specifically identified 2,000–4,000 FU as the safe and effective dose range. Doses above this range were not associated with additional benefit and carry a higher risk of excessive blood thinning.
Effective Dose Range
2,000–4,000 FU/day
Studies Reviewed
Multiple RCTs and observational studies
Safety Note
Higher doses not recommended without medical supervision
Journal
Integrative Medicine, Vol. 16
Our 4,000 FU dose sits at the top of the clinically validated range. This review directly supports our decision not to use 8,000–10,800 FU. These statements have not been evaluated by the FDA.
See the Difference

Real Numbers. Real People.

These are actual results shared by verified RiseVitals customers after 8 weeks of consistent daily use. Individual results vary — but the pattern is consistent enough that we stand behind every bottle with a 60-day guarantee.

Before
168/94
Week 0
After 8 Weeks
124/78
Week 8

*Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Blood pressure monitor showing healthy reading
Non-GMO Verified Gluten Free No Artificial Additives Third-Party Lab Tested GMP Certified Japanese-Origin Nattokinase 4,000 FU Clinical Dose K2 (MK-7) Included Non-GMO Verified Gluten Free No Artificial Additives Third-Party Lab Tested GMP Certified Japanese-Origin Nattokinase 4,000 FU Clinical Dose K2 (MK-7) Included
Ready to Support Your Heart?
Join 13,418+ customers — 50% off today only
Your Journey

What to Expect, Week by Week

This isn't a quick fix — it's a daily habit that builds over time. Here's what most customers notice in the first two months.

WK
1–2
Weeks 1 – 2
Easy Start
  • Simple daily capsule with your morning meal
  • The enzyme starts helping your blood flow more freely
  • K2 begins moving calcium toward your bones
WK
3–4
Weeks 3 – 4
Daily Balance
  • Feeling more energised and less fatigued
  • Hands and feet may feel warmer — a sign of better circulation
  • Most customers notice the first changes around week 3
WK
5–8
Weeks 5 – 8
Heart & Circulation Support
  • Blood pressure readings trending healthier
  • Arteries becoming more flexible and responsive
  • 79% of customers see measurable BP improvements by week 8
WK
8+
Week 8 and Beyond
Long-Term Wellness
  • Ongoing cardiovascular and bone health support
  • Consistent daily use maintains the cumulative benefits
  • Many customers report their doctor noticing the difference
Ready to Support Your Heart?
Join 13,418+ customers — 50% off today only
Real Stories

Real Stories, Real Results

Verified customer reviews — unedited and unfiltered.

Dorothy M.
Dorothy M.
3 weeks ago · Age 71
★★★★★
My Doctor Asked What I Changed
"I was skeptical — I've tried so many supplements. But after 6 weeks, my doctor looked at my blood pressure reading and actually asked what I had changed. I told him about RiseVitals and he said to keep doing whatever I was doing. That was enough for me."
✓ Verified Purchase
Robert J.
Robert J.
1 month ago · Age 68
★★★★★
Off One of My Blood Pressure Meds
"Vietnam vet here. I had been on blood pressure medication for over 15 years. After 3 months on RiseVitals, my doctor reduced one of my prescriptions. I'm not saying it replaces medication — but it clearly made a difference my doctor could see."
✓ Verified Purchase
Linda K.
Linda K.
2 months ago · Age 66
★★★★★
168/94 to 124/78 in 8 Weeks
"I'm an engineer so I track everything. My blood pressure had been creeping up for two years. After 8 weeks on RiseVitals, I went from 168/94 to 124/78. I've checked it every day. The numbers don't lie."
✓ Verified Purchase
Carol B.
Carol B.
3 months ago · Age 65
★★★★★
Finally Sleeping Through the Night
"After my husband's heart attack last year, I became obsessed with my own heart health. I couldn't sleep from the anxiety. Since starting RiseVitals, I feel like I'm actually doing something proactive. And my numbers have improved. I feel calmer."
✓ Verified Purchase
Frank T.
Frank T.
6 weeks ago · Age 74
★★★★★
My Cardiologist Couldn't Believe It
"After 3 months on blood pressure medication with terrible side effects, I started researching natural alternatives. My cardiologist was initially sceptical about nattokinase. At my last appointment, she said my numbers looked like someone 10 years younger. She's now recommending it to other patients."
✓ Verified Purchase
George W.
George W.
5 weeks ago · Age 70
★★★★★
Wish I'd Found This Years Ago
"I've been on the supplement merry-go-round for years. Fish oil, CoQ10, magnesium — all fine but nothing moved the needle on my blood pressure. RiseVitals is the first thing that has made a measurable difference. The K2 addition makes complete sense to me as well."
✓ Verified Purchase
Ready to Support Your Heart?
Join 13,418+ customers — 50% off today only
Discover the Science

Why Experts Trust Nattokinase

Daily heart health
Daily Heart Health

A Daily Habit Your Heart Will Thank You For

Cardiovascular health is not built in a day — it is the result of consistent, daily choices. RiseVitals Nattokinase + K2 is designed to fit seamlessly into your morning routine: one capsule, once daily, with food. No complex regimens, no multiple pills, no timing windows.

  • Supports healthy blood pressure already within the normal range
  • Promotes arterial flexibility and healthy circulation
  • K2 keeps calcium in your bones — not your arteries
  • Gentle on the stomach — no harsh compounds
60
Day Guarantee

Try It Risk-Free for 60 Days

If you are not completely satisfied with RiseVitals Nattokinase + K2 for any reason, contact us within 60 days of your purchase and we will refund every penny — no questions asked, no hassle, no fine print. We stand behind this formula because we know it works.

Claim Your 50% Discount Now
🛡 60-day money back guarantee — no questions asked
The Dose Problem

Why 4,000 FU + K2 Outperforms 10,800 FU Alone

More nattokinase is not always better. Here is why the dose and the formula both matter.

RiseVitals
4,000 FU + K2
Budget Brands
2,000 FU
High-Dose Brands
8,000–10,800 FU
Nattokinase Dose 4,000 FU (clinical dose) 2,000 FU — underdosed 8,000–10,800 FU — too much
Includes K2 (MK-7)
Matches Clinical Research Dose ✗ Too low to work ✗ Above what studies used
Blood Thinning Risk ✓ Safe at 4,000 FU ✓ Safe at 2,000 FU ⚠ May thin blood too much
Third-Party Tested Rarely Rarely
Japanese-Origin Nattokinase Unknown origin Unknown origin
60-Day Money Back Guarantee Rarely Rarely

⚠ At very high doses (8,000–10,800 FU), nattokinase may thin the blood too aggressively — especially if you're already on blood thinners. Most clinical studies use 2,000–4,000 FU. We use 4,000 FU — the highest dose backed by research — and add K2 so the formula works harder without needing to go higher.

Supports natural blood flow
Clinically backed ingredients
K2 keeps calcium out of arteries
Third-party tested every batch
No prescription required
No side effects at 4,000 FU
Treats symptoms, not the cause
No transparent testing
No K2 — calcium goes to arteries
Inconsistent quality
Prescription dependency (meds)
Known side effects (meds)
RiseVitals vs. The Alternatives

Why Nattokinase Is Different

CoQ10 gives you energy. Fish oil reduces inflammation. Blood pressure meds tell your vessels to relax — adding extra lanes so blood can still get through.

None of them clear what's causing the slowdown.

Nattokinase helps break down fibrin — the sticky protein that builds up in blood vessels over time. That's the gap nothing else fills. And K2 makes sure calcium goes to your bones, not your artery walls.

Nothing else does both.

  • Clinically backed ingredients at the right dose
  • Noticeable results within 4–8 weeks
  • Long-term cardiovascular and bone wellness
  • Clean, high-quality formula — no fillers
Try Risk-Free Today
🛡 60-day money back guarantee
Transparency Matters

We're Serious About Honest Answers

Below you'll find answers to the most common questions about nattokinase, the 4,000 FU dose, K2, and how we ensure quality in every bottle.

Most clinical studies on nattokinase use between 2,000 and 4,000 FU. 4,000 FU is the top of that range — the highest dose with solid research behind it. Products at 8,000–10,800 FU go beyond what studies have tested, and at those levels nattokinase can thin the blood too aggressively, especially if you're on blood thinners. We chose 4,000 FU deliberately. And by adding K2 (MK-7), we get better results than higher-dose formulas that skip it entirely.
K2 does something most people don't know about: it tells your body where to put calcium. Without enough K2, calcium can end up in your artery walls instead of your bones — making your arteries stiff and less flexible over time. Nattokinase helps your blood flow freely. K2 keeps your arteries from hardening. Together, they tackle heart health from two angles at once — which is why we added K2 instead of just increasing the nattokinase dose.
Most customers start noticing more energy and better circulation within 2–4 weeks. Blood pressure changes usually show up between weeks 6 and 8. A published clinical study found significant blood pressure improvements after 8 weeks of daily use. Take one capsule with food each morning, and give it at least 8 weeks before judging the results.
Fish oil and CoQ10 are both good supplements — but they do different things. Fish oil helps with inflammation. CoQ10 supports energy in your cells. Neither one helps your blood flow more freely or keeps calcium out of your arteries. Nattokinase + K2 fills a gap that most heart supplements leave open. Many of our customers take it alongside what they already use.
If you're on prescription blood thinners — like warfarin or similar medications — please check with your doctor first. Nattokinase helps your blood flow more freely, which can add to the effect of blood thinners. For most people who aren't on blood thinners, 4,000 FU is a safe and well-studied dose. When in doubt, ask your doctor — they may actually be impressed you're asking.